【摘要】 在寻找大环内酯类抗生素的过程中,运用萃取、硅胶薄层层析和重结晶等分离纯化技术,从吸水链霉菌L-892发酵液中分离得到两个小组份L-892-3和L-892-4.应用¹H、^1sC-NMR、MS、IR、UV等光谱法测定了它们的化学结构。分别鉴定抗生素L-892-3、L-892-4为methymycin和cyclizidine。更多还原

【Abstract】 In the course of screening for macrolide antibiotics, by means of extraction, TLC (silica gel)?recrystallization and so on, two minor components antibiotic L-892-3,L-892-4 were isolated from the fermentation broth of a strain of Streptomyces.Based on their spectral evidences and physicochemical properties,antibiotic L-892-3, L-892-4 have been ndentified as methymycin and cyclizidine,respectively.更多还原