【摘要】 在pH4的介质中以荧光分光光度法测定诺氟沙星,采用激发波长327nm、发射波长450nm.在浓度0.08～1.6μg/ml的范围内荧光强度与浓度呈良好的线性关系。荧光强度稳定,测定结果与非水滴定法基本一致。并探讨了诺氟沙星体内血药浓度的测定。更多还原

【Abstract】 In acid medium (pH4.0), norfloxacin was determined by spectrofluorometry with excitation wavelength 327nm and emission wavelength 450nm. The concentration of its solution in the range of 0.08 to 1.6μg/ml was in good linear relationship with its fluorescent intensity which remained stable for 24 hours. The results were in agreement with those from non-aqueous titration. The proposed method has been studied in the determination of norfloxacin in rabbit plasma.更多还原