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上油剂T—65A急性毒性与诱变性
A STUDY OF THE ACUTE TOXICITY AND IN VIVO MUTAGENICITY OF T—65A
【摘要】 本文对表面活性剂T—65A(用作上油剂)的急性毒性与诱变性进行了研究。急性试验表明小白鼠吸入LC50为58640.815mg/m3,属低毒类。其毒性主要作用于气管和肺。微核试验实验组与阴性对照比较有非常显著差别(P<0.01)。精子畸形试验高浓度组与阴性对照比较有显著差别(P<0.05)。提示T—65A有诱变作用。
【Abstract】 Acute toxicity and mutagenicity studies of a surface active agent T—65A(used as a glazing agent)were carried out.Theacute toxicity test showed that LC50 is 58640.815mg/m3.The bronchi and the lungs were mainly affected.The micronucleustest showed highly significant difference between the experimental group and control group (p<0. 05).It suggests that T-65A might be a mutagenic substance.
- 【文献出处】 中华劳动卫生职业病杂志 ,Chinese Journal of Industrial Hygiene and Occupational Diseases , 编辑部邮箱 ,1993年01期
- 【被引频次】4
- 【下载频次】14