【摘要】 作者对6例血管免疫母细胞淋巴结病患者的淋巴结HE染色病理切片进行观察,发现其基本病理特征为小血管显著增生,以免疫母细胞为主的多种免疫细胞浸润,伴有细胞间及小血管壁有无定型嗜酸性物质沉积。其组织化学染色PAS及派若宁均阳性。免疫组织化学染色:4例免疫母细胞内IgG、IgM阳性,5例Kappa、Lambda染色阳性。这说明本病是一种活跃的免疫反应,而不是真正的肿瘤。有3例其细胞内风疹病毒抗原阳性,表明某些血管免疫母细胞淋巴结病与风疹病毒有密切关系。更多还原

【Abstract】 The pathological slices were made for the lymph nodes in 6 patients with angioimmunoblastic lymphodenopathy. In HE staining,the fundamental pathological charactoristics were remarkable microvascular proliferation,obvious iramunoblastic cells in filtration and many other kinds of immune cells infiltration accompanied by nondefinite eosinophilic substance deposition in microvessesl. In histochemical staining, PAS and Peroning were both positive. In immunohistochemical staining,IgG、IgM in immunoblast cells were positive in 4 cases,Kappa and Lambda positive in 5 cases. The above findings showed that the disease (AIBL) is a kind of active immune reaction,but not real carcinoma. In 3 cases, Intracellular rubella virus antigens were positive, which indicated there was close relationship of AIBL to rubella virus.更多还原