节点文献

重症肝炎末梢血T细胞亚群分布的研究

Study of the Peripheral Blood T Lymphocyte Subtype in Fulminant Hepatitis

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 周子文刘沛王兆荃董祥家吕先科

【Author】 Zhou Ziwen, Liu Pei, Wang Zhaoquan, et al (Dept. of Infectious Disease, The Second Affiliated Hospital)

【机构】 中国医科大学附属第二医院传染科中国医科大学附属第二医院免疫室

【摘要】 本文应用单克隆抗体APAAP法检测了重症肝炎末梢血中T细胞亚群的分布。结果:重症肝炎末梢血中CD3+,和CD8+ T细胞百分率较急性肝炎明显降低(P<0.01);重症肝炎死亡病例CD8+T细胞百分率随病情加重而下降,生存例CD8+T细胞百分率在病程中无明显变化。上述结果提示:重症肝炎的发生可能与CD8+T细胞大量聚集肝组织内有关。

【Abstract】 We investigated the peripheral brood T lymphocyte subtype in patients with fulrainant hepatitis and acute hepatitis by APAAP using monoclonal antibody. The findings presented in this study: (1) The percents of CD+3 and CD+5 T lymphocytes in cases with fulminant hepatitis were significantly lower than that in acute hepatitis (P<0.01). (2) The percent of CD+8 T lymphocyte in dead cases with fulminant hepatitis had descended following the exacerdation of this disease and no change of CD+8 T lymphocyte in survival cases. The results suggest that CD+6T lymphocyte gathered a great in liver may be involved in the development of fulminant hepatitis.

【基金】 国家自然科学基金
  • 【文献出处】 中国医科大学学报 ,Journal of China Medical University , 编辑部邮箱 ,1993年04期
  • 【被引频次】1
  • 【下载频次】12
节点文献中: 

本文链接的文献网络图示:

本文的引文网络