【摘要】 25例连续换瓣患者分成两组观察自身输血对体外循环时血小板和凝血因子的保护。结果表明,体外循环时血小板数量明显减少,血小板聚集功能减退。应用自身输血后能保护部分血小板的数量和功能。本文提示术后胸腔心包引流量与放自身血量呈负相关。更多还原

【Abstract】 From October 1990 to January 1991, 25 patients underwent heart valve replacement were observed for the efficacy of autotransfusion to protect platelet and coagulation factors, and to reduce bleeding after cardioputmonary bypass. In group A of 12 cases, blood was drained by way of a small tube from the right auricle to a plastic reservoir after heparization (20-25ml/kg) with group B of 13 cases as control. The drained blood was autotransfused after cardiac resuscitation. platelet counts, platelet aggregation, fibrinogen, AT3, PLG and AT-PL were determined after heparization and after protamin infusion. Drainage volume was recorded from postoperation to 6 o’clock next morning. It was found that platelet counts in group A and B reduced by 35.17% and 50.80%, while platelet aggregation time prologned by17.04% and 31.69% respectively. The other parameters showed no significant change. Drainage volume from chest, pericardium and mediastinum was negatively correlated with the volume of autotransfusion.更多还原