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瓦松甙的强心作用及其对血流动力学的影响
Cardiotonic Activity of Orostachysside and Its Effects on Hemodynamics
【摘要】 从景天科植物流苏瓦松的花叶中提得的瓦松甙可使离体兔心房收缩振幅增高;使在体蟾蜍心输出量和作功显著增加;能增强在体兔心多种心肌收缩性能和泵血功能指标:增大左室压力变化速率峰值(LVdp/dt max)和在共同最高等容量收缩压时的心肌收缩成分的缩短速度(VCE-CPIP),缩短左室从开始收缩到开始射血的时间(t~dp/dtmax),心率减慢,左室作功增加。
【Abstract】 Orostachysside extracted from Orostachys fimbriatus, increased the amplitude of isolated rabbits auricles; It increased the output and work of toads’ hearts in vivo.The experimental results on rabbits hearts in vivo showed that orostachysside can increase the maximum rate of left ventricular pressure rise(LVdp/dt max)and the maximum velocity of contractile element, shortening in isovolumic condition (Vce-CPIP)and duration from the beginning of contraction of left ventricle to blood shooting(t-dp/dt max), and slow down the heart rate.
- 【文献出处】 中草药 ,Chinese Traditional and Herbal Drugs , 编辑部邮箱 ,1993年11期
- 【分类号】R285.5
- 【被引频次】9
- 【下载频次】13