【摘要】 从鄂北贝母Fritillaria ebeiensis中提得的新生物碱鄂贝定碱ebeiedine,经小鼠氨水引咳和豚鼠枸橼酸引咳实验证明,具有显著的镇咳效果,作用强度强于可待因,且有用量小,毒性低的特点,是一种很有开发前途的新的天然止咳药。更多还原

【Abstract】 A new steroidal alkaloid-ebeiedine isolated fiom Fritillaria ebeiensis was shown to have significant antitussive action on cough induced by ammonia liquor in mice and cough induced by citric acid in guinea-pig. The pharmacological tests revealed that ebeiedine is preferable to codeine in its small dose, low toxicity and nonaddictive. It is postulated that ebeiedine may be developed as a new potent antitussive drug.更多还原