【摘要】 从浙江磐安产东贝母鳞茎中分得6个化合物,分别鉴定为浙贝甲素(Ⅰ)、浙贝乙素(Ⅱ),异浙贝甲素(Ⅲ)、浙贝双酮(Ⅳ)、β-谷甾醇、胡萝卜甙(Ⅵ),均为首次从该植物中得到,其中Ⅳ系首次从天然界获得。东贝母中主要镇咳成分Ⅰ、Ⅱ的含量高于常用中药浙贝母。更多还原

【Abstract】 Six compounds were separated from the bulbs of Fritillaria thunbergii var.chekiangensis cultivated in Pannan, Zhejiang Province.Their structures were identified as peimine(Ⅰ),Peim-inine(Ⅱ), isoverticine(Ⅲ), verticindione (Ⅳ) ,β-sitosterol(Ⅴ)and daucosterol(Ⅵ)on the basis of spectral analysis and chemical conversion of Ⅰ～Ⅳ. They all were isolated from this plant for the first time. Among them, Ⅳ was obtained for the first time from natural sources.The contents of main anticough components Ⅰ and Ⅱ in the cultivated sPecies are higher than the traditional medicine F.thunbergii Miq..更多还原