【摘要】 本文试用家兔作HCMV感染致病机制模型研究,用家兔荧光法及病毒再分离技术考证了感染期间的病毒血症动态。观察到兔在原发性病毒感染后的第13无病毒首先在单核细胞(MC)、淋巴细胞(LC)中显现,并向血浆排放病毒,进而随血道播散至全身组织,引起相应靶器官感染致病。更多还原

【Abstract】 This paper is a study on the result of animal model with HCMV. Rabbits were inoculated with HCMV-AD₁₆₉ strain. The duration of viremic stage of rabbits infected with HCMV was studied by means of immunoflourescent assays and reisolation of the virus. Specific flourescence for HCMV anti- gen was first observed in both monocytes and lymphocytes in the blood on 13th day,and released the virus to the plasma. It was indicated that HCMV was disseminated to rabbits body, thus caused target or- gans infection.更多还原