【摘要】 本文以20名消化系统疾病病人和111名3～6岁健康幼儿为对象,检测眼结膜印迹细胞变化,并与血清维生素A浓度、维生素A相对剂量反应(RDR)进行比较,结果90％印迹细胞正常的病人血清维生素A浓度>0.7μmol/L,70％印迹细胞异常的病人血清维生素A浓度≤0.70μmol/L,经统计学处理,差异有极显著性意义(P<0.01);111名幼儿中有97.5％印迹细胞正常者的血清维生素A浓度>1.05μmol/L,64.2％印迹细胞异常者的血清维生素A≤1.05μmol/L,差异有极显著性意义(P<0.01)。故认为眼结膜印迹细胞法是一项简便,快速,有效的评价机体维生素A营养状况的指标,适合基层推广应用。更多还原

【Abstract】 Ocular signs and serum vitamin A concentration are commonly used tor the diagnosis of vitamin A deficiency. Recently, impression cytology was suggested as a method for early detection of vitamin A status. Twenty patients with normal eyes and digestive disease, and 111 children with normal eyes were evaluated by serum vitamin A concentration, relative-dose-response and conjunctival impression cytology test. About 90% of the patients with normal conjunctival impression cytology has normal vitamin A status. About 70% of the patients with abnormal conjunctival impression cytology has abnormal vitamin A status despite their seemingly normal clinical ocular examination, and so did the children. These results suggest that impression cytology can identify individuals with preclinical vitamin A deficiency.更多还原