【摘要】 从中国特有植物四川轮环藤(Cyclea sutchuenensis Gagnep.)根中除分得已知的轮环藤碱(Ⅰ)和异粒枝碱(Ⅱ)外,还分离得到两种新双苄基异喹啉生物碱,分别命名为异轮环藤碱(Ⅲ)和四川轮环藤辛碱(Ⅳ)。经物理常数和波谱数据分析鉴定,证明Ⅲ为轮环藤碱的差向异构体,Ⅳ系一种新型的8-12′,12-7′首尾双氧桥双苄基异喹啉生物碱。更多还原

【Abstract】 In addition to the known cycleanine (Ⅰ) and d-isochondodendrine (Ⅱ), two novel bisbenzylisoquinoline alkaloids named isocycleanine (Ⅲ) and sutchuenensine (Ⅳ) have been isolated from the roots of Cyckea sutchuenensis Gagnep grown wild in Sichuan province, China. Ⅲ was established as the epimer of Ⅰ and Ⅳ, as a new type of head-to-tail bisbenzylisoquinoline alkaloid with two diarylether bridges in between C-8 to C-12′ and C-12 to C-7′ on the basis of physical constants and spectral data (UV, IR, ELMS, ~1HNMR and NOEDS).更多还原