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马缨丹根的三萜成分研究

STUDIES ON TRITERPENOID CONSTITUENTS OF THE ROOTS OF LANTANA CAMARA

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【作者】 潘文斗李毓敬麦浪天大谷和弘笠井良次田中治于德泉

【Author】 WD Pan, YJ Li, LT Mai, KH Ohtani~*, RT Kasai~*, O Tanaka~* and DQ Yu~(**)(South China Institute of Botany, Academia Sinica , Guangzhou 510650; ~*Institute of Pharmaceutical Sciences, Hiroshima University School of Medicine; ~(**)Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050)

【机构】 中国科学院华南植物研究所广岛大学医学部综合药学科中国医学科学院药物研究所 广州 510650广州 510650北京 100050

【摘要】 从马缨丹(Lantana camara L.)根中分离到八个三萜成分,通过光谱(UV,IR,1HNMR,13CNMR,MS)分析和理化常数测定,分别鉴定为lantanolic acid(Ⅰ),22β-O-angeloyl-lantanolic acid(Ⅱ),oleanolic acid(Ⅲ),22βO-angeloyt-oleanolic acid(Ⅳ),22β-O-senecioyl-oleanolic acid(Ⅴ),22β-hydroxy-oleanolic acid(Ⅵ),19α-hydroxyursolic acid(Ⅶ),3β-isovaleroyl-19α-hydroxyursolic acid(Ⅷ)。Ⅱ系首次从植物中分离到。Ⅷ是新化合物,命名为lantaiursolic acid。

【Abstract】 Eight triterpenoids were isolated from the roots of Lantana camara. On the basis of their chemical properties and spectral data (UV, IR, MS, 1HNMR, 13CNMR), they were identified as lantanolic acid (Ⅰ), 22β- O- angeloyl- lantanolic acid (Ⅱ), oleanolic acid (Ⅲ), 22β-O- angeloyl-oleanolic acid (Ⅳ), 22β- O- senecioyl- oleanolic acid (Ⅴ), 22β- hydroxy- oleanonic acid (Ⅵ), 19α-hydroxy-ursolic acid(Ⅶ) and 3β-isovaleroyl-19α-hydroxy-ursolic acid (Ⅷ). Ⅱ was obtained for the first time from plant. Ⅷ is a new compound named lantaiursolic acid.

【关键词】 马缨丹马缨丹熊果酸
【Key words】 Lantana cameraLantaiursolic acid
  • 【文献出处】 药学学报 ,Acta Pharmaceutica Sinica , 编辑部邮箱 ,1993年01期
  • 【被引频次】14
  • 【下载频次】210
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