【摘要】 应用健康成人脾LAK 细胞及天然白细胞介素（N-IL-2）局部及全身输注治疗恶性肿瘤21例,其中11例为癌性胸腹水病人。每次输注LAK 细胞0.9～1.1×10⁹和N-IL-2 2万～3万u,5次为一疗程。经临床观察3～12月后证明,在缓解病人症状,控制癌性胸腹水,提高患者免疫功能,改善病人全身状况及增强机体抗肿瘤能力等方面均取得了较好疗效。治疗前后外周血单个核细胞（PMBC）的LAK 样活性及OKT₄/OKT₈比值均明显提高。治疗中除轻度发热、腹痛外未见明显毒副作用。更多还原

【Abstract】 Twenty one patients with malignant tumour were studied in this group.Among them,there are 11 patients having malignant pleural effusion or ascites.0.9～1.1×10⁹ LAK cells and 20,000～300,00u N-IL-2 were given locally or systemically for 5 times.Onfollow up 3 to 12 months,malignant pleural effusion or ascites were controlled.Peripheralblood monogranular cells and OKT₄/OKT₈ value were increased.No obvius side effectswere observed except mild fever and abdoninal pain.It suggested that allogeneic spleniclymphocytes are the satisfactory source of LAK cells.更多还原