【摘要】 小鼠在45℃高温环境下暴露15min,其网状内皮系统对碳粒的廓清作用明显降低,血清溶血素含量显著下降,绵羊红细胞（SRBC）诱发的迟发型超敏反应明显受到抑制.应激前15min人参根总皂甙（GRS）50、100 mg·kg^-1,ip,对小鼠的免疫功能有保护作用,可使热应激小鼠网状内皮系统对碳粒的廓清作用免于下降,防止血清溶血素含量的降低,迟发超敏反应不受抑制.更多还原

【Abstract】 The present study has demonstrated that in heat environment (45>>>>, 15min),the clearance of reticuloendothelial system (RES) of mice on iv charcoal particles were decreased apparently; serum hemolysin concentration were diminished notably; delayed type hypersensitivity (DTH) reaction induced by sheep red blood cell (SRBC) were inhibited obviously. Ginseng root saponins (GRS) 50, 100 mg ??? kg-1ip at 15min before the heat-stressprotected the immunity of mice from inhibitory effects induced by the heat-stressor. The suppression of the clearance of RES on charcoal particles,serum hemolysin concentration as well as DTH reaction induced by SRBC were all abolished by GRS.更多还原