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国产和进口氧氟沙星治疗伤寒和副伤寒的疗效比较

Comparison of therapeutic effects between domestic and imported ofloxacin in treating typhoid and paratyphoid fever

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【作者】 黄建荣龚正毛伟叶伟东

【Author】 HUANG Jian-Rong, GONG Zheng, MAO Wei1, YE Wei-Dong1 (The First Affiliated Hospital of ZheJiang Medical University, Hangzhou ,310003) Zhe Jiang Xinchang Pharmaceutical Limited Company, Xinchang 312500)

【机构】 浙江医科大学附属第一医院浙江省新昌制药股份有限公司浙江省新昌制药股份有限公司 杭州 310003杭州 310003新昌 312500新昌 312500

【摘要】 伤寒、副伤寒共54例,以国产氧氟沙星治疗26例(男性13例,女性13例;年龄26±s 7a),用进口氧氟沙星治疗28例(男性19例,女性9例;年龄28±9a)。剂量均为300mg, po, bid。疗程7d。结果:2组临床有效率均为100%,细菌阴转率分别为96%和100%。随访2mo均未见复发病例。提示2药治疗伤寒、副伤寒的疗效相同(P>0.05)。

【Abstract】 A controlled study of therapeutic effects between domestic and imported ofloxacin in 26 patients(M 13, F 13; age 26 ± 7 a) and 28 patients(M 19, F 9; age 28 ± 9a) with typhoid and paratyphoid fever respectively was done. The dosage were all 300 mg, bid, po, for 7 d. The results showed that the total response rate were all 100%, and the bacterial eradication rate were 96% and 100% respectivelv The therapeutic effects between the two drugs were not statistically different(P>0.05).

【关键词】 氧氟沙星伤寒副伤寒药物评价
【Key words】 ofloxacintyphoidparatyphoid feversdrug evaluation
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