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滤纸干血ELISA在华支睾吸虫病流行病学调查中的应用

STUDY ON THE APPLICATION OF FILTER PAPER DRY BLOOD ELISA TO THE EPIDEMIOLOGICAL SURVEY OF CLONORCHIASIS SINENSIS

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【作者】 张翠芬崔惠儿彭业恒蔡文安

【Author】 Zhang Cuifen1, Cuei Huie1, Peng Jieheng2, Cai Minan21 Institute of Antiparasitic Diseases of Guangdong Province (Guangzhou 510300)2 Diseases-Preventive and Health Center of sansui County

【机构】 广东省寄生虫病防治研究所广东省三水市预防保健中心广东省三水市预防保健中心 广州 510300广州 510300

【摘要】 两种华支睾吸虫成虫可溶性抗原作ELISA与粪检的阳性符合率均接近90%。现场调查结果表明,粪检与ELISA的阳性检出率无显著差异。检查村民2309人,阳性符合率为89.3%,阴性符合率为92.8%。患者的感染度和血清抗体滴度与阳性符合率有密切关系。重度感染者阳性符合率高达97.9%,而轻度感染者阳性符合率仅为60.60%。感染度越重血清抗体滴度越高。

【Abstract】 THe positive correlativity of fecal examination and soluble antigen from two kinds of adult clonorchis sinensis was nearly 90%. Results of field survey showed that there was no obvious difference between the positive rates of fecal examination and that of ELISA. The positive correlativity was 89. 3%, and the negative correlativity was 92. 8% with 2309 cases. There was close relationships between positive correlativity and the clonorchis sinensis egg density (amount of egg/per gram fece) of the infected people. The positive correlativity of seriously infected people was as high as 97. 9%. while the positive correlativity of those with lighter infection was only 61. 1%. The more serious the infection, the serum antibody titers. was much higher.

【关键词】 华支睾吸虫病ELISA粪便检查
【Key words】 Clonorchis sinensisFecal examinationELISA.
  • 【文献出处】 中国血吸虫病防治杂志 ,Chinese Journal of Schistosomiasis Control , 编辑部邮箱 ,1993年06期
  • 【被引频次】1
  • 【下载频次】21
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