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乙型肝炎病毒宫内感染的探讨
Reseach the newborn baby infected hepatitis B virus in utero
【摘要】 对HBsAg(+)母亲34例和HBsAg(-)母亲21例,在产时和所生新生儿进行系列血清观察,用ELISA法检测HBVM(HBsAg、抗-HBs、HBeAg、抗-HBe、抗-HBc),同时测肝功能(SALT、TTT),并随访到1月龄。发现HBsAg(+)母亲组持续抗原血症1例,HBVM阳性伴ASLT升高8例,提示宫内感染率为26.5%(9/34)。HBsAg(-)母亲组HBVM及肝功均正常。两组差异显著(X~2=4.85;P<0.05)。
【Abstract】 Studied the hepatitis B serological examination of 34 HBsAg positive and 21 negative mothers and their newborn babies. HBsAg, anti-HBs, HBeAg, anti-HBe and anti-HBc were determinated with ELISA. Antigeneamia appears in 4 babies and 5 babies are found anti-HBc positive in maternal HBsAg positive group, the above babies are companied with sGPT raise, while all the babies in maternal HBsAg negative group are normal in examination. In HBsAg positive maternal group, the rate of hepatitis B of the newborn babies (9/34) sug- gested that the HBV infection is transmitted in utero.
- 【文献出处】 新生儿科杂志 ,The Journal of Neonatology , 编辑部邮箱 ,1993年05期
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