【摘要】 取慢性肺原性心脏病（肺心病）急性加重期10例,做口服葡萄糖耐量试验（OGTT）,并测定应激性激素及胰岛素（Ins）。选健康人10例作对照。结果表明:肺心病急性加重期血清皮质醇、FT₄、HGH分泌增加,Ins分泌增加,血糖升高,显示Ins抵抗,机体对糖的利用减低。而胰高糖素分泌正常并未参与该病的应激过程。说明该病在急性加重期宜适当限制糖的摄入,皮质激素也并非必需常规使用。更多还原

【Abstract】 Ten patients with cor-pulmonale and 10 normal controls were investigated on acute exacerbation stage, oral glucose tolerance test （OGTT） was performed and stress hormones were evaluated. Our data indicated that the serum levels of cortisol, free T₄ （FT₄）, human growth hormone （HGH）, and insulin （Ins） were elevated as well as glucose, but the level of glucagon （Glu） was unchanged, suggesting that the glucose utilization was decreased probably due to insulin resistance, and glucagon was not involved in the stress reaction. We think that carbohydrate should be properly restricted and corticosteroids should not be administered routinely on the acute exacerbation stage of the disease.更多还原