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用51Cr白细胞粘附抑制实验检测乙肝特异性转移因子的抗原特异性
Antigenic Specificity of Specific Transfer Factor to Hepatitis B Virus Studied by 51Cr-Leukocyte Adherence Inhibition Assay
【摘要】 以51Cr白细胞粘附抑制(51Cr-LAI)实验为指标,研究了乙肝特异性转移因子的抗原特异性。结果表明:只有抗原特异性转移因子(TFHBV)可以使未经免疫的鼠脾淋巴细胞对HBsAg产生LAI反应,而非特异性转移因子(TFn)无此作用。证明TFHBV中确含有促进抗原依赖性细胞免疫反应成分,具有抗原特异性。
【Abstract】 Antigenic specificity of specific transfer factor to hepatitis B virus (TFHBV) had been studied by 51Cr-leukocyte adherence inhibition assay(51Cr-LAI).The present results suggested that TFHBV could produce LAI reaction for nonimmunized mouse spleen lymphocyte on HBsAg, but non-immunized transfer factor did not. TFHBV consist of agents of reaction that promote specific cellular immunity and have antigenic specifcity.
【关键词】 白细胞粘附抑制实验;
转移因子;
乙型肝炎病毒;
【Key words】 leukocyte adherence inhibition assay transfer factor hepatitis B virus;
【Key words】 leukocyte adherence inhibition assay transfer factor hepatitis B virus;
- 【文献出处】 天津医药 ,Tianjin Medical Journal , 编辑部邮箱 ,1993年11期
- 【被引频次】1
- 【下载频次】15