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应用鸡卵细胞大量制备多克隆抗体
Mass Preparation of Polyclonal Antibody with Hen Egg cells
【摘要】 用三种不同来源的抗原(基因工程HBVe、HCV核心区抗原和GM—CSF)免疫鸡,观察血清及卵黄中特异性抗体的应答,结果经免疫的鸡对这3种抗原均有免疫应答,所产卵的卵黄中可测出大量的有活性的抗体。提示鸡源性抗体在生物制品开发应用方面有一定的前景。
【Abstract】 Specific antibody responses in the serum and yolk of hens immunized with recombinant HBeAg, HCV core antigen and human GM-CSF antigen were observed. The result showed that all the three antigens could induce specific antibodies in immunized hens, and significamt quantity of active an- tibodies could be detected in yolk of eggs laid by the hens. It indicated that antibodies derived from hens opened up prospects for development and application of biologieals.
- 【文献出处】 中国生物制品学杂志 ,Chinese Journal of Biologicals , 编辑部邮箱 ,1993年04期
- 【被引频次】15
- 【下载频次】62