【摘要】 1991年对58645名1～7岁儿童进行了乙脑活疫苗流行病学效果观察,接种乙脑活疫苗组29639人,发生乙脑2例,发病率为6.75/10万;未接种组29006人,发生乙脑46例,发病率158.59/10万,二者差异显著(x~2=39.49,P<0.005),疫苗当年保护率95.74％、保护比1:23.49,高于国内灭活疫苗报告的结果,同时,活疫苗对病情的轻重和转归有良好的影响.而且使用简便安全。更多还原

【Abstract】 58 645 children aged 1~7 were selected for an epidemiologic study on the efficacy of Japanese Encephalitis (JE) live vaccine in 1991. Only 2 of the 29 639 vaccinated children suffered from JE, the morbidity was 6.75/100 000. In the unvaccinated group, 46 among 29 006 children contracted the disease and the morbidity was 158.59/100 000. The protective ratio and the protective rate of the live vaccine were 1:23. 49 and 95. 74%, respectively. It showed significant difference be tween the two groups (x~2=39. 49, p<0. 005). The result indicated that the protective efficacy of JE live vaccine was superior to that of JE live vaccine as reported in this country. The vaccine showed good effect on the severity and prognostic of JE. The live vaccine is also convenient and safe to adminstrate.更多还原