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在非胰岛素依赖型糖尿病中优降糖和中草药CMH疗效评价对比

A COMPARISON BETWEEN THE EFFICIENEIES OF GLYBURIDE AND CMH ON NIDDM PATIENTS

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【作者】 史虹莉朱禧星钟学礼洪绮霞

【Author】 Shi Hong-li et al Huashan Hospital,Shanghai Medical University,Shanghai,200032

【机构】 上海医科大学华山医院糖尿病研究室上海医科大学华山医院糖尿病研究室

【摘要】 本文采用随机双盲法观察优降糖和/或中草药 CMH 治疗糖尿病的疗效。40例非胰岛素依赖型糖尿病患者随机分成4组,A 组予安慰剂,B 组予优降糖,C 组予优降糖和 CMH,D 组予 CMH,疗程为三个月。研究结果表明:(1)优降糖能降低果糖胺、空腹和餐后血糖水平,提高餐后1小时胰岛素水平。(2)CMH 能降低果糖胺和空腹血糖水平。(3)优降糖和 CMH 合用无明显毒副作用,且降糖效果更强。

【Abstract】 It is important for a NIDDM patient to normalize his blood glucose.Apart fromcalorie restriction and diet modification,hypoglycemic treatment is of necessity.40patients were devided into 4 groups at random.Using double blind test each group wastreated with drugs or placebo:group A with placebo,group B with glyburide,group Cwith glyburide and CMH,and group D with CMH.Fructosamine,triglyceride,high-density lipoprotein,blood glucose and plasma insulin level before,1 hour,2 hours afterthe meal were measured before and after the 3 months drug treatment.By statisticaltest,we found that 1)glyburide can lower fructosamine and blood glucose level before,1 hour,2 hours after the meal and the plasma insulin level 1 hour after the meal wasincreased;2)CMH can decrease fructosamine and blood glucose before the meal;and3)combination of glyburide and CMH does not cause toxic effect,its hypoglycemiceffect seems more potent than that of glyburide alone.

【关键词】 非胰岛素依赖型糖尿病优降糖中草药
【Key words】 NIDDMGlyburideChinese Medical Herb
  • 【文献出处】 上海医学 ,Shanghai Medical Journal , 编辑部邮箱 ,1993年07期
  • 【被引频次】2
  • 【下载频次】31
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