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CellCul-20A反应器的丝网间液体交换速率及氧传递模型

Liquid Exchange and Oxygen Transfer Models in CellCul-20A Bioreactor

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【作者】 王斯靖陈因良俞俊棠

【Author】 Wang Sijing Cben Yinliang Yu Juntang (Research Institute of Biochemical Engineering, East China University of Chemical Technology, Shanghai 200237)

【机构】 华东化工学院生化工程研究所

【摘要】 针对笼式通气搅拌生物反应器的特点,本文提出了一种简单可信的测量丝网内外液体交换速率的实验方法,根据此方法,在CellCul-20A生物反应器中得出了通过丝网的液体交换速率关联式: 单层丝网:Qs=1.93×10-5N1.81+1.13×10-4UG0.61 (Ⅰ) 双层丝网:Qs=3.42×10-5N1.49+1.46×10-4UG0.68 (Ⅱ)并在此基础上,建立了合适的深层通气的氧传递模型,得到: 理论分析和实验结果表明,增大丝网内的液体体积和提高丝网内的氧传递速率,可以有效地提高反应器的体积氧传递系数。

【Abstract】 In this paper, based on the mass transfer characteristics of the stirred bioreactor with a cage aeration device, a novel experimental method and the correlations of liquid exchange rates have been presented for measuring the liquid exchange rates tbrougb the metal screen. On these bases, a mathematical model of oxygen transfer on deep aeration has been established. The theoretical analyses and the experimental results show that the total oxygen transfer capacity can be enhanced by increasing the cage volume and oxygen transfer efficiency inside the cage.

  • 【文献出处】 生物工程学报 ,Chinese Journal of Biotechnology , 编辑部邮箱 ,1993年04期
  • 【被引频次】5
  • 【下载频次】34
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