【摘要】 分析111例中枢神经系统白血病(CNSL),发生率为急性白血病的18.7%,其中以急性淋巴细胞性白血病(ALL)最高。在ALL患者中,CNSL可发生于任何时期,而急性非淋巴细胞性白血病(ANLL)绝大多数发生在白血病进展期。第1次发生CNSL时脑脊液蛋白含量越高,则第2次发生CNSL距离第1次发作的时间越近。预防性鞘内注射3次以上,可降低CNSL发生率,对CNSL的治疗,以MTX+Ara-c+头颅照射为优。更多还原

【Abstract】 This paper reports the clinical analysis of 111 cases of central nerous system leukemia (CNSL) in our hospital during 1981—1992. The relationship of its recurrence with the cellular type and the duration of the disease and the treatment were discussed. We also found the higher the protein content of the CSf, the shorter the time between two occurrences of CNSL.更多还原