【摘要】 本实验对照观察了山莨菪碱预防家兔油酸性肺水肿时血气及肺系数的变化,静脉注入油酸造成家兔急性肺水肿,出现严重呼吸困难,血气参数（PaO₂,PaCO₂）均显著下降（P<0.01）,两肺明显肿大、出血,肺系数增大（P<0.01）。而预先用山莨菪碱进行预防,则能稳定血气指标。PaO₂及 PaCO₂无明显变化（P>0.05）,肺系数明显低于肺水肿组（P<0.01）。实验显示了山莨菪碱对家兔油酸性肺水肿的预防作用及可能机制。更多还原

【Abstract】 The effect of anisodamine on blood gas and lung coefficent in pulmonaryedema induced by oleic acid was observed in rabbits.Acute pulmonary edema occurred to therabbits after injecting oleic acid,serious dyspnea.PaO₂ and PaCO₂ obviously lower（p<0.01）.The lung coefficent increased（p<0.01）.But in anisodamine—preventive group,blood gas pa-rameter had little decline（p>0.05）.The lung coefficent was obviously lower than that inpulmonary edema group（P<0.01）.From the above we can see that administeringanisodamine can prevent rabbits from acute pulmonary edema induced by oleic acid.更多还原