【摘要】 本实验对照放免,应用单克隆抗体酶免法对15例绒毛膜上皮癌患者化疗期间进行尿hCG半定量及定量测定,每例检测10～12次。同时对15例正常足月分娩产妇产后第2～8天血及尿放免和血及尿酶免同时测定hCG 浓度,进一步对比放免及酶免结果以及血、尿的hCG 量的关系.结果表明:放免与酶免结果相符,且尿hCG 含量高于血清。酶免定量法具有灵敏、方便、快速、准确等优点,可望能替代放免应用于滋养细胞肿瘤的诊断、疗效观察和随访。此法可在基层医院推广应用,随访病人可用酶免法作自我监护。更多还原

【Abstract】 Urinary hCG of 15 cases of choriocarcinoma receiving chemotherapywas determined(10-12 dtns./case)both semi-quantitatively and qunatitativelyby monoclonal antibody enzymoimmuno assay(EIA)and radioimmunoassay(RIA).At the same(?)time,blood hCG and u(?)ine hCG contents of 15 normal fulltermparturients were determined by EIA and RIA 2～8 days after parturition forcomparison.RIA and EIA yielded identical (?)esults,with urine (?)CG higher thanserum hCG.EIA,being more sensitive,convenient,rapid,accu(?)ate andavailable in basic hospitals,had the prespect of replacing RIA in the diagnosis,evaluation of therapeutic effects and follow-up of choriocarcinoma.In follow-upcases,pateints may make use of EIA for self-monitoring.更多还原