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慢性肺心病急性加重期患者血清丙二醛、超氧化物岐化酶及全血硒含量的研究

Studies on contents of serum MDA,SOD and whole blood Se in chronic pulmonary heart disease during acute aggravated period

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【摘要】 我们测定了106例慢性肺源性心脏病急性加重期患者及78例健康对照组血清丙二醛(MDA),超氧化物岐化酶(SOD)及全血硒(Se)的含量。肺心病组血清 MDA 明显高于对照组(P<0.01);血清 SOD 及全血硒 Se 含量则明显低于对照组(P<0.01)。结果提示:自由基及微量元素 Se 可能参与了慢性肺心病的病理生理过程。

【Abstract】 We determined the contents of serum MDA,SOD and whole blole blood Se in 106 eases of chronic pulmonary heart disease during the acute aggravated period,with healthy control of 78 cases.The content of serum MDA in pulmonary heart disease was obviously higher than that of the control(P<0.01);the contents serum SOD and whole blood Se were obviously lower than the control(P<20.01).The results suggested that the free radicals and the trace element Se might be associated with the chronic pulmonary heart disease in its pathological and physiological processes.

【关键词】 肺心病; 丙二醛; 超氧化物岐化酶; 硒;
【Key words】 chronic pulmonary heart disease; MDA; SOD; Se;
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