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卒中平对动脉硬化性脑梗塞患者血浆TXB2和6-酮-PGF1α含量的影响
THE EFFECTS OF STROKE-SUPPRESSION ON THE PLASMA TXB2 AND 6-KETO-PGF1a LEVELS OF THE PATIENTS WITH ARTERIOSCLEROSTIC CEREBRAL INFARCTION
【摘要】 本文采用卒中平,一种在我国古方基础上经科学筛选后组成的并经临床证实对治疗脑梗塞有确切疗效的纯中药制剂,治疗23例急性动脉硬化性脑梗塞患者,以观察对治疗前后血浆TXB2和6-酮-PGF1α含量的影响。结果表明治疗后患者血浆中TXB2含量显著下降(P<0.05)。提示卒中平治疗脑梗塞的途径之一可能是通过降低血浆TXA2,调节PGI2-TXA2失衡状态,减轻TXA2对中枢神经系统的损害而实现的。
【Abstract】 23 patient s with arteriosclerostic cerebral infarction were treated by stroke-suppression. The data showed that the plasma TXB2 le-vels of these patients were decreasedafter treatment. But the plasma 6-keto-PGF1. levels were no significant cha-nge. We suggest that the therapeuticeffeciency of stroke-suppression on thepatients with arteriosclerostic cerebralinfarction may be related to the modi-fied effect of the plasma TXA2 andPGI2 levels.
【关键词】 卒中平;
脑梗塞;
TXB2;
6-酮-PGF1α;
【Key words】 Stroke-suppeession; Cerebral infarction; TXB2 6-KETO-EGF1α;
【Key words】 Stroke-suppeession; Cerebral infarction; TXB2 6-KETO-EGF1α;
- 【文献出处】 华西药学杂志 ,West China Journal of Pharmaceutical Sciences , 编辑部邮箱 ,1993年01期
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