【摘要】 采用 Beckman 系统分析法和 ELISA 法对30例急性根尖周炎患者循环抗体水平进行了测定,结果显示 IgG,IgA,IgM 值正常而 IgE 值升高,表明急性根尖周炎的发生很可能与 I 型变态反应有关。采用直接凝集法和 ELISA 法对其中 IgE 值明显升高的8例血清与其感染根管内厌氧菌的特异性进行了测定,结果表明感染根管内厌氧菌能使宿主致敏,但由于是内源性感染,宿主的免疫应答趋于平衡,引起血中 IgE 升高的特异抗原有待进一步查明。更多还原

【Abstract】 The circulating antibody levels of the patients with acute periapical lesions,the total specific serum antibodies and specific IgE antibody against the anaerobes isolated from the infected root canals were determined by means ofBeckman ICS,ELISA and Direct Coagulation methods.The results indicated that the host’s immunogic responsesto anaerobic bacteria played an important role in the acute clinical symptoms while resisted the bacteria’s infec-tion.The acute periapical lesions might be concerned with the type I anaphylactic hypersensitivity reaction.Thespecific agents to elicit the serum IgE antibodies elevated were still unclear and needed further examinations.更多还原