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急性根尖周炎患牙根管内厌氧菌的细菌学研究——第2报 急性根尖周炎患者循环抗体水平及血清特异性抗菌抗体的研究
Bacteriological Study on Anaerobic Bacteria Isolated from Infected Root Canals of Teeth with Acute Periapical Lesions Section 2:The Study of the Circulating Antibody Levels of Patients with Acute Periapical Lesions and the Specific Serum Antibodie
【摘要】 采用 Beckman 系统分析法和 ELISA 法对30例急性根尖周炎患者循环抗体水平进行了测定,结果显示 IgG,IgA,IgM 值正常而 IgE 值升高,表明急性根尖周炎的发生很可能与 I 型变态反应有关。采用直接凝集法和 ELISA 法对其中 IgE 值明显升高的8例血清与其感染根管内厌氧菌的特异性进行了测定,结果表明感染根管内厌氧菌能使宿主致敏,但由于是内源性感染,宿主的免疫应答趋于平衡,引起血中 IgE 升高的特异抗原有待进一步查明。
【Abstract】 The circulating antibody levels of the patients with acute periapical lesions,the total specific serum antibodies and specific IgE antibody against the anaerobes isolated from the infected root canals were determined by means ofBeckman ICS,ELISA and Direct Coagulation methods.The results indicated that the host’s immunogic responsesto anaerobic bacteria played an important role in the acute clinical symptoms while resisted the bacteria’s infec-tion.The acute periapical lesions might be concerned with the type I anaphylactic hypersensitivity reaction.Thespecific agents to elicit the serum IgE antibodies elevated were still unclear and needed further examinations.
- 【文献出处】 华西口腔医学杂志 ,West China Journal of Stomatology , 编辑部邮箱 ,1993年02期
- 【被引频次】3
- 【下载频次】43