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1990~1992年郑州地区婴幼儿轮状病毒感染的流行病学研究

AN EPIDEMIOLOGY STYDY OF ROTAVIRUS IN INFENT IN ZHENGZHOU FROM 1990 TO 1992

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【作者】 周建华邓莹李泳高东培高铁铮

【Author】 Zhou Jian-hua Deng Ying Li Yong Gao Dong-pei Gao Tie-zen (Department of pediatrics,The first Affiliated Hospital,Henan Medical University,Zhengzhou 450052)

【机构】 河南医科大学第一附属医院儿科郑州市第四人民医院河南医科大学第一附属医院儿科 郑州 450052郑州 450052450007

【摘要】 自1990年5月~1992年12月逐月对郑州市及郊县1686例婴幼儿急性腹泻患儿粪便标本。用聚闪烯酰凝胶电泳(PAGE)法进行轮状病毒(HRV)病原学研究。检测结果表明,3年轮状病毒总感染率为31.02%,其中长型轮状病毒占66.16%,短型占33.48%。感染多发于2岁以内小儿,尤以1~2岁高发;与性别无关。该地区全年均有 HRV 肠炎发生,感染率与月平均气温及降水量呈负相关关系(r_气=-0.3908,P<0.05;r_降=-0.5327,P<0.002),以10、11月(气温7.7~15.7℃,降水量1~46mm)最高(56.49%),以7~9月最低(2.74%)。本结果为HRV 肠炎的流行病学监测和预防提供了科学依据。

【Abstract】 Between May 1990 and December 1992,a total of 1686 stool specimens were collected from Zhengzhou infants and children with acute gastroenteritis and tested for the presence of rotavirus by the methods of polyacrylamide gels electrophoresis(PAGE).Results showed that incidence of human rotavirus infection in infants and young children with diarrhea was 31.0%.66.1% were identified as strains belonging to long type and 33.8% were identified as strains belonging to short type.Rotavirus infection was usually taken place in 2 years and especially ranged from 1 to 2 years. The infection frequency appeared not to be related to sex.In the regin,human rotavirus enteritis were epidemic all around year.The infection frequency was correlated negatively with mean temperature and amount of rain every month(r=-0.3908,P<0.05;r=-0.5327,P<0.002,respectively).It was the hightest from October to Nevember(temperature 7.7~15.7℃,amount of rain 1~46mm, 51.49%)and the lowest from July to september(2.74%).The results provide scientific foundation for the epidemic supervision and prevention of human rotavirus enteritis.

【关键词】 轮状病毒腹泻婴幼儿流行病学
【Key words】 rotavirusdiarrheainfantepidemiology
  • 【文献出处】 河南医学研究 ,Henan Medical Research , 编辑部邮箱 ,1993年02期
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