【摘要】 本文对老年人血清中可溶性白细胞介素-2受体（SIL-2R）浓度、外周血单个核细胞（PBMC）经 PHA 刺激后白细胞介素-6（IL-6）产生和增殖能力做了研究;同时检测了血清中免疫球蛋白和 C₃含量。结果显示,老年人血清 SIL-2R水平（878.57±256.54U/ml）比青年人 SIL2R 水平（583.65±171.29U/ml）显著升高（P<0.05）,IL-6产生能力也显著升高（P<0.001）,而老年人淋巴细胞增殖反应明显降低（P<0.001）。老年人血清中免疫球蛋白浓度与青年人相比,IgG 无显著差异（P>0.05）;IgM、IgA 均显著升高（P<0.001;P<0.01）。老年人血清中 C₃浓度比青年人明显升高（P<0.001）。这些结果提示,老年人的细胞免疫和体液免疫功能均有改变。更多还原

【Abstract】 Concentration of soluble IL-2R（SIL-2R）in serum,IL-6 production and proliferative responses of PHA stimulated peripheral blood mononuclear cells（PBMC）,as well as the levels of serum immunoglobulin and C₃ derived from aged humans were studied.SIL-2R levels in sera from aged （878.57±256.54U/ml）were significantly higher than in sera derived from young subjects（583.65 171.29U/ml）,P<0.05.The capability of IL-6 production were also significantly increased,while the proliferative responses of lymphocyte were decreased in aged（P<0.001）.Concentration of IgM, IgA were found significantly being elevated（P<0.001）in aged,but no difference were found in IgG （P>0.05）.The concentration of serum C₃ were significantly elevated as compared with the young subjects（P<0.001）.These results showed the cellular immunity and humoral immunity were both changed in aged humans.更多还原