【摘要】 应用聚合酶链反应检测了53例HBsAg(-)慢性肝病患者血清中的HBV DNA。结果为:53例患者中38例阳性,占71.70%;其中慢性肝炎15例,阳性率83.33%(15/18);肝炎后肝硬化7例,阳性率58.33%(7/12);原发性肝癌16例,阳性率69.57%(16/23)。结果提示在HBsAg(-)慢性肝病中,仍以乙肝病毒感染为主。更多还原

【Abstract】 Serum HBV DNA was tested in 53 HBsAg-negative chronic liver disease patients with the poly-merase chain reaction (PCR). In the 53 cases of chronic liver disease,we found HBV DNA in 15 ofthe 18 patients with chronic active hepatitis,7 of the 12 patients with cirrhosis of the liver and 16 ofthe 22 patients with primary liver cancer. In total,HBV DNA was found in 38 cases,including 16 ofthe 18 cases with positive anti-HBc alone, 6 of the 9 cases with positive anti-HBs and 16 of the 26 cas-es without any HBV serologic markers. We conclude from the results that in patients of HBsAg-nega-tive chronic liver disease,the etology may still be hepatitis B virus.更多还原