【摘要】 报道放射性锶促排药S186(乙酰丙胺二膦酸钙钠盐)连续肌注30d对狗微量元素Cu、Zn、Mn含量的影响。微量元素的测定采用PE3030原子吸收分光光度仪。实验观察到连续肌注S186(50,100,200mg/kg)30d对Beagle狗组织中(心、肝、脾、肺、肾、小肠等)微量元素(Cu、Zn、Mn),除肝Cu含量与对照组相比有增高外,其余均无明显变化。更多还原

【Abstract】 This paper reports the influence of a radiostrontium decorporating agents, S186 (calcium sodium N- acetylproplysmine 1, 1- diphosphonate), on trace elements in internal organs of dogs. The trace elements contents were determined with a PE- 3030 atomic absorption spectrophotometer. Compared with the control group, the trace elements (Cu, Zn and Mn) contents and the Cu/ Zn ratio in organs of Beagle dogs after intramuscular injection of S186 for 30 days did not change obviously except the Cu content in the liver increased.更多还原