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母体巨细胞病毒感染致幼儿听力异常的研究
Auditory Dysfunction Effect of Maternal Cytomegalovirus Infection on The Infants
【摘要】 随机检查322例孕妇,取其宫颈分泌物、产后乳汁及新生儿尿液培养分离巨细胞病毒(CMV),阳性率为12/322例(3.72%).对其中CMV感染母亲的8例幼儿进行脑干听觉诱发电位(BAEP)测定,与8例母亲未感染之幼儿对比,结果表明,感染组中5例出现听功能损害,P<0.01,同时检查两组婴幼儿尿液,各出现4例CMV阳性,母亲阳性组4例幼儿均发生听力异常,母亲阴性组4例中仅1例异常,提示先天性巨细胞病毒感染对婴幼儿的危害性比后天感染对婴儿的损害大。
【Abstract】 The specimens of cervix secretion and oreast milk randomly from 322 pregnant wemen and those of urine from their newborn infants were cultured for cytomegalovirus. Specific inclusion bodies were found in 12 cases. Brainstem auditory evoked potentials (BAEP)were examined, among 8 of their infants and the other 8 whose mothers were uninfected with cytomegalovirus. The results demostrated loss of sensitivity in 5 cases of the inrection group and hearing dysfunction in only 1 of the uninfected group, P<0.01. It also suggested that the incidence for auditory defect in congenital CMV infection is 3 times than acquired.
【Key words】 cytomegalovirus; brainstem auditory evoked potentials; auditory defect;
- 【文献出处】 广州医学院学报 ,Academic Journal of Guangzhou Medical College , 编辑部邮箱 ,1993年01期
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