【摘要】 <正> 本实验观察家兔喂饲胱氨酸后的不同时期内,血浆PGI₂和TXA₂的动态变化特点,并对血胆固醇,胱氨酸水平和动脉壁脂质斑块形成程度进行比较,目的在于探讨胱氨酸致动脉粥样硬化的可能机制,并为临床防治冠心病提供帮助。更多还原

【Abstract】 This experiment tock 20 rabbits randomly divded into experimental （feeding with cystins）and control group. Drawing blood for biochem-icae and radioimmunoassay test in pre-experime-ntal and 4th, 8th, 12th Week days after feeding.The result discovered that the contents ofserum cystine, platelet aggregation and plasmaTXA₂ levels increased in the experimentalgroup more than that of thc contolled rabbits,but plasma PGI₂ decreased. While the contentsof total cholesterol was not Changed. Athero-scleretic plazues in the aorta was also rema-rkable incrensed. There were foamy cells piledup and by microscopic analysis. According to results of above metioned, weconclude that high-cystinemia may lead toatherosclerosis because of destroyed aorta Wall,activated platelet function and inbalance ofPGI₂-TXA₂, but not releted to lipidemialevels.更多还原