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缺血性中风患者脑脊液中β-内啡肽含量变化

Changes of CSF β-endorphin Contents in the Patients with Ischemic Stroke

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【作者】 林弘林锋叶子青慕容慎行黄一镗

【Author】 Lin Hong Lin Feng Ye Ziqing (Department of Neurology,The 1st Affiliated Hospital,Fujian Medical College,Fuzhou)

【机构】 福建医学院附属第一医院神经科福建省心血管病研究所内科福建医学院附属第一医院内科福建医学院附属第一医院神经科

【摘要】 应用放射免疫法检测50例缺血性中风患者脑脊液(CSF)中β-内啡肽(B-EP)的含量。结果表明,患者 CSF 中β-EP 明显高于对照组,且重症组的β-EP 值高于轻症组(P<0.01),发病≤4天患者的β-EP 值高于发病>4天者(P<0.05).

【Abstract】 The contents of CSF beta—endorphin in 50 patients with ischemic stroke were measured by using radioimmunoassay.The levels of beta—endorphin of stroke patients had significantly increased as com- pared with the controls(P<0.01).The beta—endorphin levels at acute stage(within 4 days after the onset of stroke)were higher(P<0.05)than those at chronic stage(more than 4 days after stroke). The patients with severe stroke had significantly higher beta—endorphin levels(P<0.01)than those with mild stroke.These results indicate that the disturbance of beta—endorphin metabolism at acute stage is related to ischemic neurologic deficits

【关键词】 缺血性中风脑脊液β-内啡肽
【Key words】 ischemic strokeCSFbeta-endorphin
  • 【被引频次】2
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