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肾脏病自身免疫机理的研究

STUDIES OF AUTOANTIBODY IN NEPHROPATHY

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【作者】 高美华; 王海燕; 邱世翠; 曲云英; 范兴忠;

【Author】 Gao Meihua,et al(Department of Microbiology, Binzhou Medical College)

【机构】 滨州医学院微生物学教研室; 滨州医学院附属医院内科;

【摘要】 本文采用间接免疫荧光技术及葡萄球菌蛋白A(SPA)花环试验对60例肾脏病患者自身抗巨噬细胞抗体、抗肾细胞抗体及抗肝细胞抗体进行观测。实验结果表明,患者血清中抗肾细胞及巨噬细胞抗体明显增高,与健康对照组相比P<0.01,差异有高度显著性。由此证明肾脏病的发生与自身免疫病理损伤密切相关。

【Abstract】 Indirect immune fluorescence technique and SPA rosette test were adopted to observe the antibody of anti-kidney cell, anti-liver cell and anti-macrophage in 60 cases of nephropathy. The results showed that the antibody of anti-kidney cell and anti-macrophage was increased in patients with nephropathy. As compared with normal group,the differences were obvious (P<0. 01). This proves that nephropathy is closely related to autoimmune hurt.

【关键词】 肾脏病; 自身抗体;
【Key words】 nephropathy; autoantibody;
  • 【文献出处】 滨州医学院学报 ,Journal of Binzhou Medical College , 编辑部邮箱 ,1993年03期
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