【摘要】 本文以单克隆抗体ELISA夹心法对26例慢性活动性乙型肝炎(CAH-B)与40例重症乙型肝炎(SH-B)患者检测了血浆可溶性白细胞介素2受体(sIL-2R).结果提示CAH-B和SH-B患者血浆sIL-2R水平明显高于对照组(P<0.0005),SH-B的sIL-2R水平高于CAH-B(P<0.05);而急性重肝、亚急性重肝与慢性重肝三者之间血浆sIL-2R水平无显著性差异,提示血浆sIL-2R水平高低与肝脏损害严重程度明显相关.HBeAg阳性组与抗-HBe阳性组血浆sIL-2R水平无明显差别(P>0.05),这似乎说明血浆.sIL-2R水平高低与HBV复制状态无关.更多还原

【Abstract】 Plasma levels of sIL- 2R were measured by ELISA in 26 patients with chronic hepatitis B (CAH-B),40 patients with severe hepatitis B(SH-B) and 17 healthy controls.The levels of sIL -2R in patients with CAH-B and SH-B were found to be significantly elevated as compared with healthy controls (P <0. 0005). The level of sIL-2R in patients with SH-B was much higher than that in patients with CAH-B. These differences were independent of hepatitis B virus (HBV) replication,because there was no difference between HBeAg-positive patients and HBeAg -negative patients.更多还原