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急性白血病形态学和免疫学及细胞遗传学分型分析
AN ANALYSIS OF MORPHOLOGIC, IMMUNOLOGIC AND CYTOGENETIC CLASSIFICATION IN CASES WITH ACUTE LEUKEMIA
【摘要】 本文从形态学、免疫学和细胞遗传学(MIC)三方面系统观察了31例初治成人急性白血病,结果表明,形态学与细胞化学符合率84%,FAB分型与免疫学分型符合率93.5%,FAB分型与MIC分型符合率为96.8%,免疫学分型与MIC分型符合率亦为96.8%。在27例AML中,淋巴细胞抗原阳性(Ly~+-AML)6例,占22.2%。31例急性白血病中染色体核型异常15例,占48.4%。
【Abstract】 We observed morphologic, immunologic, and cytogenetic classification in 31 untreated adult pati-ents with acute leukemia. It was found the correspondence rate between morphology and cytochemistrywas 84%, the correspondence rate between FAB classification and immunologic classification was93.5%, and the correspondence rate between. immunologic classification and MIC classification was96.8K. Among 27 patients with acute myelogenous leukemia (AML), six cases showed lymphocyteantigen-positive (22.2%). Of 31 cases of acute leukemia, 15 showed chromosome karyotypic abnorma-lities (48.4%). Of 13 cases of AML-M2, 5 had t(8;21). Of 8 cases of AML-M3, 3 had t(15; 17).Amnog 4 patients with acute lymphocytic leukemia, one had t(9; 22), one had t(9; 15; 22).
- 【文献出处】 北京医科大学学报 , 编辑部邮箱 ,1993年01期
- 【被引频次】13
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