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血清癌胚抗原糖抗原50在胃癌诊断中的意义

THE DIAGNOSTIC VALUE OF SERUM CEA AND CA50 IN PATIENTS WITH GASTRIC CANCER

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【作者】 胡乃中; 章礼久; 丁之平;

【Author】 Hu Neizhgng et al, Department of Gastroenterology, First Affiliated Hospital, Anhui Medical University, Hefei.

【机构】 安徽医科大学附属医院消化科; 安徽医科大学附属医院消化科;

【摘要】 本文应用放免法同时检测33例胃癌和45例胃良性病变的CEA和CA50血清值发现:胃癌组的CA50,CEA血清值较良性胃病组均有显著性差异(P<0.05)。认为CA50、CEA的血清值均可做为胃癌诊断中有用的辅助指标。进一步比较这两种抗原,胃癌中CA50的敏感性最高为63.34%,明显优于CEA的30.31%。本组CA50血清值与胃癌的大小,转移,病理分型,均无显著相关性(P>0.05)。而血清CEA在胃癌远处转移时有显著升高(P<0.05),可借此判断胃癌有否远处转移。

【Abstract】 Serum CEA and CA50 content have been measured by means of radio-immunoassay in 33 patients with gastric disease. The result shows thatthe serum CEA and CA50 content of patients with gastric cancer are. higher than in those with nonmalignant gastric disease (P<0.05). It holds thatboth serum CEA and CA50 content may be useful indexes in the diagnosis of gastric cancer. After further comparsion, we found that the diagnostic sensitivity of CA50 (63.34%) to gastric cancer is higher than that of CEA (30.31%). No relation has been found between serum CA50 content and the esistence of metastasis,pathologic type and the size of gastric lesion (P>0.05). But the serum CEA content in patients with distant metastasis increased more significantly than that in patients without metastasis (P<0.05), it seems therefore to have practical diagnostic value.

  • 【文献出处】 安徽医学 ,Anhui Medical Journal , 编辑部邮箱 ,1993年04期
  • 【被引频次】1
  • 【下载频次】18
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