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消胃炎散治疗胃粘膜腺体肠土皮化生和不典型增生的临床研究

Clinical Study on Treatment of Intestinal Metaplasia and Atypical Hyperplasia of Gastric Mucosa with Xiao Wei Yan Powder

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【作者】 刘宣然韩文谦孙德荣陈景康王永汉唐文英王忠贵阎世明宋恩荣韩枚

【Author】 Liu Xuan-ran;Han Wen-qian;Sun De-rong, et al The Qingdao TCM-WM Hospital, Qingdao 266002

【机构】 青岛市中西医结合医院青岛市中西医结合医院 山东 266002山东 266002

【摘要】 本文报告应用消胃炎散治疗胃粘膜肠化和不典型增生的临床研究结果。随机分为治疗组和对照组。结果:治疗组对肠化的总有效率为91.30%,对不典型增生的总有效率为92.16%;而对照组对肠化和不典型增生的有效率分别为21.23%和14.46%。治疗组疗效显著优于对照组(P<0.01)。

【Abstract】 138 cases of intestinal metaplasia (IM) and 104 cases of atypical hyperplasia (AH) of the gastricmucosa of chronic gastritis treated with Xiao Wei Yan Powder (XWYP) were reported. Thediagnoses were based on the pathological examination of gastric antrum biopsy specimens. Thecases were randomly divided into treated group and control group. The XWYP contained Smilaxglabrae, Hedyotis diffusae, Taraxacum mongolicum, Caesalpinia sappan, Paeonia alba, Cyperus rotun-dus, Bletilla striata, Glycyrrhiza uralensis etc., and was prepared in powder form, taken orally 5-7g tid.After 2-4 month of administration, gastroscopic and pathological examinations were repeated.Results: In treated group, the total effective rate of IM was 91.3% and that of the AH was 92.16%,while in coatrol group, they were 21.3% and 14.46% respectively (P<0.01). It denoted that XWYPhad marked therapeutic effects for IM and AH. The animal experiments revealed no toxic effect, sosafety guarantee was provided for its clinical application.

  • 【文献出处】 中国中西医结合杂志 ,Chinese Journal of Integrated Traditional and Western Medicine , 编辑部邮箱 ,1992年10期
  • 【被引频次】7
  • 【下载频次】50
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