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遗传因素对儿童血压的影响

Influence of Hereditory Factor on Blood Pressure in Children A Twin Study

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【作者】 王志强欧阳镇玉冬妹

【Author】 Wang Zhiqiang School of public health,Harbin Medical University (150001)

【机构】 哈尔滨医科大学公共卫生学院儿少卫生教研室哈尔滨医科大学公共卫生学院儿少卫生教研室 (150001)(150001)

【摘要】 本文测量分析了110对同性别7~12岁双生儿童的血压,采用两种方法估计遗传度。结果发现:儿童血压的遗传度较低,HoLzinger 法估计收缩压和舒张压的遗传度分别为0.41和0.51,Chri-stian 法估计二者的遗传度分别为0.35和0.32。这一结果强调,环境因素对儿童血压的变异起着重要作用。

【Abstract】 Systolic and diastolic blood pressure were measured in 110 pairs of like-sex twins aged 7 ~2 years.Heretability of blood pressure was estimated by two different methods.Low here- tability estimates were found.Heretability esti- mations were 0.41 and 0.51 for systolic and di- astolic respectively,by Holzinger’s method, and 0.35 and 0.32 by Christian’s method.Our results emphasize the importance of environme- ntal factors in determination of blood pressure in children.

【关键词】 双胎血压遗传度
【Key words】 Twins Bloo dpressure Heretability
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