【摘要】 作者于1990年4月对吉林省长白朝鲜族自治县5个村的969名15岁及15岁以上朝鲜族居民进行了整群抽样调查及高血压病的遗传流行病学研究。结果表明:朝鲜族高血压病患病率为14.2%。高血压系多基因遗传,遗传度为50.0%。有高血压家族史者的高血压患病率显著高于无家族史者,分别为24.8%和12.5%。父母患高血压病的子女有易患倾向,尤以父母均患高血压者的子女患病危险度最高,提示遗传因素对高血压的易患性有重要作用。对婚后共同生活达15年以上的配偶收缩压进行相关分析,结果表明:夫妻收缩压呈弱相关(r=0.282),说明生活环境等后天因素对高血压的易患性变异也有一定的影响。更多还原

【Abstract】 This article is a part of the epidemiologic studies on hypertension of Chaoxian nationality over Jilin province in April 5～14,1990.All 969 men and women,aged 15 year and over,were interviewed at home.The study indicated hy- pertension is polygenic inheritance.Heretability of hypertension is 50%.Persons with and without family history of hypertension have different pr- evalance rates (24.8% vs.12.5%,p<0.01). History of hypertension of parents was pro- ved to be predictive of the development of hy- pertension.The effects of marriage on hyperte- nsion were observed.The Survey supports the point that genetic factors in the hypertension li- ability play an important role.更多还原