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原发性高血压的遗传度研究

Study of Hereditability of Essential Hypertension

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【作者】 徐剑锋王文英张国栋沈福民钱鸣钮鹰周珠芳

【Author】 Xu Jianfeng Department of Child and Adolescent Health,Shanghai Medical University (200032)

【机构】 上海医科大学儿少卫生教研室上海医科大学流行病学教研室上海医科大学卫生系89级上海市虹口区卫生防疫站上海市虹口区卫生防疫站 (200032)(200032)夜大学实习生

【摘要】 本文调查了83名原发性高血压儿童的1级亲属(183名)和2级亲属(367名)的血压值和高血压病史,同时对80名血压正常儿童的1级亲属(184名)和2级亲属(346名)进行了调查作为对照组。在对高血压的患病率进行年龄校正的标准化处理后,得到1级亲属资料计算的遗传度为70±9.8%,用2级亲属资料计算的遗传度为57±7.9%。文章对二者的差异进行了分析,并认为后者较为可靠。

【Abstract】 We investigated the blood pressure and hy- pertensive history of the first degree relatives (183) and the second degree relative (367) of 83 essential hypertension children.At the same time,we investigated these data of the first degree relatives (184) and the Second degree relatives (346) of s0 normal blood pressure chi- ldren as control group.After taken standardi- zed treatment through correcting age bias of the morbidity of essential hypertension,we got the heriditability of essential hypertertension h=70+ 9.8% by using the data of the first degree rela- tives and h=57+7.9% by using the data of the second degree relatives.The paper analysed the difference between the two hereditability and considered the (?)d is more reliable.

【关键词】 原发性高血压遗传度
【Key words】 Essential hyportension Hereditability
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