【摘要】 本文介绍了Y—BOCS量表,并用该量表对35例强迫症和41例有强迫症状的精神分裂症病人,在单独使用氯丙咪嗪治疗前作了症状严重程度评定,在疗后作了药物疗效评定,结果提示量表中“造成病人痛苦”和“病人对症状主动对抗”二项,两组病人有显著性差异(P<0.01),其余各项无显著性差异(P>0.05)。疗后的疗效评定提示,单独使用氯丙咪嗪对精神分裂症伴有的强迫症状疗效甚差,对强迫症疗效亦不够理想。作者认为Y—BOCS比以往有关量表在评定症状严重程度和评定药物疗效方面更简便更有效。更多还原

【Abstract】 In this paper,Y-BOCS was introduced and used to evaluate the severity of the symptoms in 35 patients with obsessive-compulsive disorder (OCD group I)and 4 ! schizophrenics with obsessive-compulsive symptoms (group Ⅲ) before and after being given chlorimipramine alone and the effectiveness of the agent was also assessed.It was shown that there was a significant statistically difference between group Ⅰ and group Ⅱ on two items distress of symptoms and voluntary resistance against symptoms.There were no significant differences (p>0.05) on the other items.The assessment of effectiveness of chlorimipramine suggested that chlorimipramine used alone had weaker effect on both schizophrenics with obsessive-compulsive symptoms and OCD patients.The authors considered that Y-BOCS is more effective and more convenient than other previous scales on the assessment of severity the symptoms and effectiveness of chlo-rimipramine.更多还原