【摘要】 在实验室条件控制下,中华硬蜱重复叮咬家兔后吸血量明显减少,初次叮咬后吸血增重233.78±44.71mg,第二和第三次叮咬分别下降至67.03±25.18mg和80.23±29.96mg(P<0.001)。被咬后的家兔血清经ELISA测定其体内蜱抗体(OD值0.48)较对照组家兔(OD值0.08)显著高(P<0.01)。免疫后家兔其~3H-TdR淋巴细胞转化试验和皮肤试验与对照组家兔有显著差异,表明家兔对中华硬蜱叮咬所产生的获得住免疫力,包括宿主的体液免疫和细胞免疫。更多还原

【Abstract】 This paper first reported that the immune resistance was induced in rabbits by repeated tick (Ixodes sinensis )infestation.This host resistance was expressed as a reduction in tick engorgement weight.The initial tick engorgment was 233.78±44.71mg.The second and third infestation resulted in a reduced engorgement 67.03±25.18mg and 80.23±29.96mg respectively(P< 0.01).The anti-tick antibody demonstrated with ELISA showed a dramatic increase OD values.The values of pre-infestation and post-infestation were 0.08 and 0.48 respectively (P<0.01).PHA indexes of stimulation with H-TdR lymphocyte transformation test were 48.57±31.41 (immunized rabbits) and 15.49±14.53 (control rabbits) respeetively P<0.01.Difference of skin responses between treated and control rabbits was also evident.The paper suggested that the immunce resistance of rabbits,induced by Ixodes sinensis,concern with both the host humoral immune and cell immune.更多还原