【摘要】 应用不同剂量率、不同剂量的⁶⁰Co-γ射线照射健康成人外周静脉血,培养72h后观察淋巴细胞微核率、微核细胞率以及含不同数目微核的各类微核细胞的出现几率。主要结论如下:（1）微核率、微核细胞率的剂量效应关系均为二次多项式,高剂量下需引进指数项修正;（2）由于剂量率的影响,利用微核剂量效应曲线估算得到的剂量值,存在较大的不确定度,尤其进行低剂量估算时更明显;（3）利用各类多微核细胞出现的剂量阈值和剂量率阈值的不同,可粗略估算受照剂量和剂量率范围,并可减小剂量估算的不确定度。更多还原

【Abstract】 The frequencies of micronuclei, micronucleate cell and various micronucleate cell in human lymphocytes, which had been irradiated with 60Co gamma ray at different doses and dose rates, were investigated after 72 hours of irradiation. The results are as following: (1) the relationship between dose and frequency of micronuclei or frequency of micronucleate cell is a quadratic polynominal, and at high dose the exponential correction is needed. (2) The uncertainty of estimated dose by dose-effect curve is depending on the dose rate, especially, in the low dose range the influence is remarkable. (3) By using of different thresholds of dose and dose rate for appearing micronucleate cell, the dose and dose rate received by human body can be roughly estimated and the uncertainty can be reduced.更多还原