【摘要】 为了研究体外循环(CPB)对人体免疫功能的影响,本文对CPB心脏手术成人10例(A组)、儿童9例(B组)围术期免疫功能进行了观察。两组间得出了相似的结果:除了白细胞数CPB后第1～7天内明显增多外,其余6项免疫指标在CPB第一小时后均表现免疫功能低下,术后1周才能恢复到术前水平,故此期监护要严格无菌操作,积极抗炎和支持疗法,对预防术后感染,促使患者早日康复甚为重要。更多还原

【Abstract】 In this prospective study, the perioperative immune function change of 16 patients (10 of adults, group A; 6 of children, group B) was observed to evaluate the influence of cardiopulmonary bypass (CPB) on it. Immune function tests wese made before operation and 1, 4 and 7 days after operation Similar immune function change was observed within these two groups. The results indicated that immune function was decreased significantly after CPB at first hour and recovered to preoprative level one week later, except peripheral white blood cell count was significantly increased post operatively, so aseptic manipulation should be reinforced in postoperative care, and active antiinflammatory and supporting therapy for one week after operation are important to infection prevention and early recovery.更多还原