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炙甘草汤对正常及脾虚大鼠乌头碱心律失常的影响

The Effects of "Zhigancao" Decoction(ZGCD)on Aconitine-induced Cardiac Arrhythmias in the Normal Spleen Function and Spleen Deficency Rats

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【作者】 林秀珍崔志清郭世铎张延霞

【Author】 Lin Xiu-zhen, Zhang Yan-xia, et al

【机构】 天津医学院药理教研室河北医学院邯郸分院

【摘要】 炙甘草汤预防给药对正常及脾虚组大鼠乌头碱引起的心律失常均有显著的对抗作用,与对照组比较,心律失常发生率和类型评分明显降低(P<0.05)。正常及脾虚大鼠乌头碱心律失常一旦发生,随即用炙甘草汤治疗,对正常组大鼠疗效明显,而脾虚组大鼠与对照组柑比,无明显差异。

【Abstract】 Aconitine-induced cardiac arrhythmias were shown to be preventable by prior injection of ZGCD in the normal spleen funation und spleen deficency rats. Compared with the control group, the incidenae and score of cardiac arrhythmias were significantly decreased (P<0.05). Once the aconitine-induced cardiac arrhythymias occured, there was an obvious antiarrhythmic action in the normal spleen function group following injection of ZGCD, but there was no difference in the spleen deficency rats under the same conditions compared with the controls.

【关键词】 炙甘草汤脾虚乌头碱心律失常
  • 【文献出处】 中草药 ,Chinese Traditional and Herbal Drugs , 编辑部邮箱 ,1992年12期
  • 【分类号】R285.5
  • 【被引频次】5
  • 【下载频次】25
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